INTRODUCTION OF ANTIMALARIAL DRUGS Antimalarial drugs are used to prevent and treat malaria. It is anti-parasitic chemical agent. Most antimalarial drugs target is the erythrocytic stage of malaria infection. As we have studied about different types of species of malaria parasite, so for kill that all the species or treatment there are so many drugs are available in the market. Antimalarial drugs can be classified on the basis of chemical structure and mechanism of action which is given below. CLASSIFICATION Chemical structure Mechanism of action 1. ACCORDING TO CHEMICAL STRUCTURE Chemical class Drugs name (generic name) 4-Aminoquinolines Chloroquine, Amodiaquine, Piperaquine Quino...
INTRODUCTION OF MALARIA Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected mosquito named female anopheles mosquito. This is communicable disease means when infected mosquito bites person and person gets infected. Now when uninfected mosquito bites this infected person then this uninfected mosquito gets infected and this infected mosquito bites another person, this is how the disease transmit person to person via bites of infected mosquito. And in such a way this cycle goes. LIFE CYCLE OF PLASMODIUM PARASITE Life cycle of plasmodium is completed in two hosts and it is called digenetic. These are two hosts given below. 1) female anopheles mosquito 2) human beings Here female anopheles mosquito is a primary or definitive host as a sexual phase of the malaria parasite occurs in the mosquito, while human beings are secondary or intermediate host as asexual phase of malaria parasite occur in the man. Half cycle of ...